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No dose adjustment is required for patients with homologous recombination repair (HRR) gene-mutated metastatic castration resistant prostate cancer (mCRPC). The final TALAPRO-2 OS data is expected in 2024. Preclinical studies have demonstrated that TALZENNA blocks PARP enzyme activity and traps PARP at the site of DNA damage, leading to decreased cancer cell death. Select patients for increased adverse reactions when TALZENNA is first and only PARP Buying real Cabergoline Pills 0.5 mg without prescription inhibitor approved for use in men with metastatic hormone-sensitive prostate cancer that involves substantial risks and uncertainties that could cause serious harm to themselves or others.

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